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Administration to pregnant and nursing women: Since teratogenicity was denied in animal tests but safety in pregnant women has not been established, Hyruan III injection should be cautiously administered to pregnant women or women having possibility to be pregnant only when it is judged that benefits of treatment exceed a possibility of danger.
Since it has been proved Hyruan III injection is excreted into breast milk in animal tests, nursing should be avoided during the administration of it.
